A short video explaining the programme
About us
Maternal and Child Health (MCH) is critical because it is a key determinant of the health of a society and the focus of our program is on finding effective solutions that have major public health implications. Our strategy is to encourage discovery research that is inspired by societal need and innovation which is driven by new or existing knowledge in order to create applications that can go back to the society.
Collaborators
Institutional Collaborators
Consortium
Consortium
Publications
Recent Publications
Placental Proteomics Reveals an Elevated Level of Aldo-Keto Reductase 1-B1, Highlighting Its Potential Role in Spontaneous Preterm Birth
Kharbanda N, Biswas A, Tiwari A, Tailor P, Saha S, Wadhwa N, Thiruvengadam R, Salunke DM, Bhatnagar S, Garbh-Ini Study Group, Kshetrapal P, Maiti TK. 2025 10.1021/acs.jproteome.4c00698.
Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis.
Monangi NK, Xu H, Fan YM, Khanam R, Khan W, Deb S, Pervin J, Price JT, Kaur L; INTERBIO-21st Study Consortium; Al Mahmud A, Thanh LQ, Care A, Landero JA, Combs GF, Belling E, Chappell J, Chen J, Kong F, Lacher C, Ahmed S, Chowdhury NH, Rahman S, Kabir F, Nisar I, Hotwani A, Mehmood U, Nizar A, Khalid J, Dhingra U, Dutta A, Ali SM, Aftab F, Juma MH, Rahman M, Ahmed T, Islam MM, Vwalika B, Musonda P, Ashorn U, Maleta K, Hallman M, Goodfellow L, Gupta JK, Alfirevic A, Murphy SK, Rand L, Ryckman KK, Murray JC, Bahl R, Litch JA, Baruch-Gravett C, Sopory S, Chandra Mouli Natchu U, Kumar PV, Kumari N, Thiruvengadam R, Singh AK, Kumar P; GARBH-Ini study team; Alfirevic Z, Baqui AH, Bhatnagar S, Hirst JE, Hoyo C, Jehan F, Jelliffe-Pawlowski L, Rahman A, Roth DE, Sazawal S, Stringer JSA, Ashorn P, Zhang G, Muglia LJ. 2024 10.1016/j.ajcnut.2023.10.011
Previse preterm birth in early pregnancy through vaginal microbiome signatures using metagenomics and dipstick assays.
Talukdar D, Sarkar M, Ahrodia T, Kumar S, De D, Nath S, Jana P, Verma J, Mehta O, Kothidar A, Yodhaanjali JR, Sharma K, Bakshi S, Singh U, Kshetrapal P, Wadhwa N, Thiruvengadam R; Garbh-Ini study group; Nair GB, Bhatnagar S#, Mukherjee S, Das B#. 2024 10.1016/j.isci.2024.111238
Incidence of and risk factors for small vulnerable newborns in north India: a secondary analysis of a prospective pregnancy cohort.
Thiruvengadam R, Ayushi, Murugesan DR, Desiraju BK, Misra S, Sharma D, Subbaian SS, Mehta U, Singh A, Sharma S, Khurana A, Mittal P, Chellani H, Bharti R, Tripathi R, Sopory S, Kshetrapal P, Salunke DM, Natchu UCM, Ramji S; GARBH-Ini study team; Wadhwa N, Bhatnagar S#. 2024 10.1016/S2214-109X(24)00212-2
Development and external validation of Indian population-specific Garbhini-GA2 model for estimating gestational age in second and third trimesters.
Veerendra P. Gadekar VP, Damaraju N, Xavier A, Thakur SB, Vijayram R, Desiraju BK, Misra S, GARBH-Ini Study Group, Wadhwa N, Khurana A, Rathore S, Abraham A, Rengaswamy R, Benjamin S, Cherian AG, Bhatnagar S, Thiruvengadam R, Himanshu Sinha H. 2024. 2024 10.1016/j.lansea.2024.100362.
Post-natal gestational age assessment using targeted metabolites of neonatal heel prick and umbilical cord blood: A GARBH-Ini cohort study from North India.
Ramasamy T, Varughese B, Singh M, Tailor P, Rao A, Misra S, Sharma N, Desiraju K, Thiruvengadam R, Wadhwa N; GARBH-Ini Study Group; Kapoor S, Bhatnagar S#, Kshetrapal P. 2024 10.7189/jogh.14.04115
Automatic Image Guidance for Assessment of Placenta Location in Ultrasound Video Sweeps
Gleed AD, Chen Q, Jackman J, Mishra D, Chandramohan V, Self A, Bhatnagar S, Papageorghiou AT, Noble JA 2023 10.1016/j.ultrasmedbio.2022.08.006
Genome-wide temporal landscaping of DNA methylation in pregnant women delivering at term: a GARBH-InI study
Das J, Wadhwa N, Natchu UCM, Thiruvengadam R, Kshetrapal P, Bhatnagar S#, Majumder PP, Maitra A 2023 10.2217/epi-2023-0145
The challenges in gestational weight gain monitoring in low and middle income settings
Thiruvengadam R, Desiraju BK, Sachdev HS, Bhatnagar S# 2023 10.1038/s41430-023-01292-w
Genome-wide temporal landscaping of DNA methylation in pregnant women delivering at term: a GARBH-InI study.
Das J, Wadhwa N, Natchu UC, Thiruvengadam R, Kshetrapal P, Bhatnagar S, Majumder PP, Maitra A. 2023 10.2217/epi-2023-0145
The challenges in gestational weight gain monitoring in low and middle income settings
Thiruvengadam R, Desiraju BK, Sachdev HS, Bhatnagar S. 2023 10.1038/s41430-023-01292-w
Genetic variants associated with spontaneous preterm birth in women from India: a prospective cohort study. . Apr . doi:
Bhattacharjee E, Thiruvengadam R, Ayushi, Das C; GARBH-Ini Team; Wadhwa N, Natchu UCM, Kshetrapal P, Bhatnagar S, Majumder PP, Maitra A. 2023 10.1016/j.lansea.2023.100190
Immunological Changes in Pregnancy and Prospects of Therapeutic Pla-Xosomes in Adverse Pregnancy Outcomes
Devvanshi H, Kachhwaha R, Manhswita A, Bhatnagar S, Kshetrapal P 2022 10.3389/fphar.2022.895254
Longitudinal changes in serum immune markers during normal pregnancy in a North-Indian population
Kaushal K, Ayushi, Sharma N, Wadhwa N, Misra S, Bhatnagar S, Desiraju BK, Thiruvengadam R, Sopory S; GARBH-Ini study group 2022 10.1111/aji.13531
Longitudinal profile of sHLA-G during pregnancy and its association with small for gestational age births in North Indian pregnant females: A nested case-control study
Sehgal S, Vyawhare S, Bhatnagar S#, Kshetrapal P; GARBH-Ini study group 2022 10.1111/aji.13504
Development of second and third-trimester population-specific machine learning pregnancy dating model (Garbhini-GA2) derived from the GARBH-Ini cohort in north India. Preprint from
Damaraju N, Xavier A, Vijayram R, Desiraju BK, Misra S, Khurana A, Wadhwa N, GARBH-Ini Study Group, et al 2022 10.1101/2021.10.02.21264450
Development of deep learning model to estimate gestational age in the 2nd and 3rd trimesters of pregnancy: A prospective cohort study in North India
Mishra D, Varun V, Gosain M, Mukesh M, Khurana A, Noble A, Natchu UCM, Wadhwa N, Thiruvengadam R, Desiraju BK, Bhatnagar S 2022 10.1002/uog.25022
Immunological Changes in Pregnancy and Prospects of Therapeutic Pla-Xosomes in Adverse Pregnancy Outcomes
Devvanshi H, Kachhwaha R, Manhswita A, Bhatnagar S, Kshetrapal P. Immunological Changes in Pregnancy and Prospects of Therapeutic Pla-Xosomes in Adverse Pregnancy Outcomes. Front Pharmacol. 2022 10.3389/fphar.2022.895254
Longitudinal changes in serum immune markers during normal pregnancy in a North-Indian population.
Kaushal K, Ayushi, Sharma N, Wadhwa N, Misra S, Bhatnagar S, Desiraju BK, Thiruvengadam R, Sopory S; GARBH-Ini study group. 2022 10.1111/aji.13531
Gestational weight gain trajectories in GARBH-Ini pregnancy cohort in North India and a comparative analysis with global references
Ramachandran T, Desiraju BK, Natchu UCM, Wadhwa N, Sachdeva K, Misra S, Parmar N, Juyal M, Mittal P, Bharti R, Tripathi R, Ramji S, Sachdev HS, Bhatnagar S#, GARBH–Ini study team 2021 10.1038/s41430-021-01040-y
The Vaginal Microbial Signatures of Preterm Birth Delivery in Indian Women
Kumar S, Kumari N, Talukdar D, Kothidar A, Sarkar M, Mehta O, Kshetrapal P, Wadhwa N, Thiruvengadam T, Desiraju BP, Nair GB , Bhatnagar S#, Mukherjee S, Das B, GARBH-Ini Study Group 2021 10.3389/fcimb.2021.622474
Pattern of variation in DNA methylation during pregnancy among mothers who delivered preterm in the GARBH-Ini cohort
Das J, Bagchi I, Ghosh S, Wadhwa N, Nachu UC, Thiruvengadam R, Kshetrapal P, Bhatnagar S#, Majumder PP, Maitra A, GARBH-Ini Team 2021 10.1101/2021.09.02.21262698
Comparison of first trimester dating methods for gestational age estimation and their implication on preterm birth classification in a North Indian cohort
Vijayram R, Damaraju N, Xavier A, Desiraju BK, Thiruvengadam R, Misra S, Chopra S, Khurana A, Wadhwa N, GARBH-Ini Study Group, Rengaswamy R, Sinha H, Bhatnagar S# 2021 10.1186/s12884-021-03807-4
Preterm Birth is Associated with Reduction of Maternal Telomere Length During Pregnancy
Sarkar S, Godara K, Sarkar S, Ghosh S, Maity A, GARBH-Ini Team, Sindhu B Bhatnagar S, Majumder P, Wadhwa N, Maitra A 2021 10.21203/rs.3.rs-197790/v1
Umbilical cord tissue is a robust source for mesenchymal stem cells with enhanced myogenic differentiation potential compared to cord blood
Mishra S, Sevak JK , Das A , Arimbasseri GA, Bhatnagar S, Gopinath SD 2021 10.1038/s41598-021-93047-5
Comparison of first trimester dating methods for gestational age estimation and their implication on preterm birth classification in a North Indian cohort
Vijayram R, Damaraju N, Xavier A, Desiraju BK, Thiruvengadam R, Misra S, Chopra S, Khurana A, Wadhwa N, GARBH-Ini Study Group, Rengaswamy R, Sinha H, Bhatnagar S# 2021 10.1186/s12884-021-03807-4
Dynamic Alteration in the Vaginal Secretory Proteome across the Early and Mid-Trimesters of Pregnancy
Kumar B, Dey AK, Saha S, Singh AK, Kshetrapal P, Wadhwa N, Thiruvengadam R, Desiraju BK, Bhatnagar S#, Salunke DM, Rashid F, Malakar D, Maiti TK; GARBH-Ini Study Group 2021 10.1021/acs.jproteome.0c00433
Vaginal Microbiome of Pregnant Indian Women: Insights into the Genome of Dominant Lactobacillus Species.
83. Mehta O, Ghosh TS, Kothidar A, Gowtham MR, Mitra R, Kshetrapal P, Wadhwa N, Thiruvengadam R; GARBH-Ini study group, Nair GB, Bhatnagar S, Das B. 2020 10.1007/s00248-020-01501-0
Protein Profile Changes in Circulating Placental Extracellular Vesicles in Term and Preterm Births: A Longitudinal Study
Menon R, Debnath C, Lai A, Guanzon D, Bhatnagar S, Kshetrapal P, Sheller-Miller S, Salomon C 2020 10.1210/endocr/bqaa009
Salivary proteome signatures in the early and middle stages of human pregnancy with term birth outcome
Dey AK, Kumar B, Singh AK, Ranjan P, Thiruvengadam R, Desiraju BK, Kshetrapal P, Wadhwa N, Bhatnagar S#, Rashid F, Malakar D, Salunke DM, Maiti TK; GARBH-Ini Study Group*. 2020 10.1038/s41598-020-64483-6
Umbilical cord tissue is a robust source for mesenchymal stem cells with enhanced myogenic differentiation potential compared to cord blood
Mishra S, Sevak JK, Das A, Arimbasseri GA, Bhatnagar S, Gopinath SD 2020 10.1038/s41598-020-75102-9
A Pregnancy Cohort to Study Multidimensional Correlates of Preterm Birth in India: Study Design, Implementation, and Baseline Characteristics of the Participants
Bhatnagar S#, Majumder PP, Salunke DM, Interdisciplinary Group for Advanced Research on Birth Outcomes—DBT India Initiative (GARBH-Ini) 2019 10.1093/aje/kwy284.
Provocative ideas on human placental biology: A prerequisite for prevention and treatment of neonatal health challenges
Sehgal S, Bhatnagar S, Pallavi SK. 2017 10.1111/aji.12656
Provocative ideas on human placental biology: A prerequisite for prevention and treatment of neonatal health challenges
Sehgal S, Bhatnagar S, Pallavi SK 2017 10.1111/aji.12656
Funding agencies
Funding agencies
Other funding support
State-of-the-Art Infrastructure
Platforms
Biorepository
State-of-the-Art Infrastructure
Biorepository is housed in an area of 2766 sq feet. All the stored biospecimens are coded with alphanumeric codes and the participants IDs are de-identified by the use of Unique Indentification code (UIC). Read more
Data Management Centre
Data Management process for Paper Data Capture
Role of the Data Management Centre: Right from the conception of the project to even after the study ends. Initially created as part of Garbhini but has already suppprted 8 studies (4 completed, 4 active) till now. Read more
